GPR45 Polyclonal Antibody, 100ul Cell Culture Dishes Dare to try today

Dare to try today

This protein is activated by PI3-kinase

This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet

Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia

2002 [PubMed 12191433])

GPR45 Polyclonal Antibody, 100ul Cell Culture Dishes Dare to try todayThis intronless gene encodes a member of the G protein coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.