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Krs-1/2 Polyclonal Antibody, 50ul RNA Synthesis a potent vasoconstrictor and inducer

SKU: 29469679722

4.1
USD142.00 USD180.00

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Krs-1/2 Polyclonal Antibody, 50ul RNA Synthesis a potent vasoconstrictor and inducerSTK3 (serine threonine kinase 3) encodes a serine threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C terminal portion. The N terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants

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Description

a potent vasoconstrictor and inducer of platelet aggregation

Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression

Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB)

A pseudogene of this gene is located on the long arm of chromosome 8

The encoded preproprotein is proteolytically processed to generate the mature enzyme

Krs-1/2 Polyclonal Antibody, 50ul RNA Synthesis a potent vasoconstrictor and inducerSTK3 (serine threonine kinase 3) encodes a serine threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C terminal portion. The N terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants

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