HtrA2 Polyclonal Antibody, 50ul[BT-AP04278] Protein Research More than a dozen pseudogenes

More than a dozen pseudogenes of NPM1 have been identified

The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking

Interacts with HABP4 and KRT1

Plays a critical role in maintaining genomic stability and cellular integrity following UV-induced genotoxic stress

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family

HtrA2 Polyclonal Antibody, 50ul[BT-AP04278] Protein Research More than a dozen pseudogenesHTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear