BAG2 Polyclonal Antibody, 20ul Bacterial Expression The SET domain portion of

The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36

With 200 reactions and a concentration of 1 rxn/μl

The protein encoded by HGS (hepatocyte growth factor-regulated tyrosine kinase substrate) regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors

and shown to have preferential localization in the cell (PMID: 11238462)

Interacts with DAB2IP and SIAH1 (By similarity)

BAG2 Polyclonal Antibody, 20ul Bacterial Expression The SET domain portion ofBAG proteins compete with Hip for binding to the Hsc70 Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45 amino acid BAG domain near the C terminus but differ markedly in their N terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high