Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser Negatively regulates its own expression

Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2

reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2

AVEN expression may be a useful tool in prognosis prediction

This gene encodes a member of the testis-specific protein Y-encoded

enteropathy

Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser Negatively regulates its own expressionLipid modulating phosphodiesterase (PubMed: 26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed: 26095358). Lacks activity with phosphocholine containing lipids, but can cleave CDP choline, and