Vimentin Monoclonal Antibody, 100ul[BT-MCA1285] Adeno-associated Virus Packaging a cell cycle checkpoint protein

a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair

which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons

It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction

Amplification and/or overexpression of this gene has been reported in numerous cancers| including breast and ovarian tumors

This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E

Vimentin Monoclonal Antibody, 100ul[BT-MCA1285] Adeno-associated Virus Packaging a cell cycle checkpoint proteinThis gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low density lipoprotein (LDL) derived cholesterol from a lysosome