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The encoded protein is a brain-specific inhibitor of angiogenesis

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2003 [PubMed 14519125])

Despite containing a histidine acid phosphatase domain| the encoded protein functions as an inositol pyrophosphate kinase| and is thought to lack phosphatase activity

CLN8 Polyclonal Antibody, 100ul Microplate Mixer and COA to ensure theThis gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER Golgi intermediate compartment. Mutations in this gene are associated with progressive epilepsy with mental retardation (EMPR), which is a subtype of neuronal ceroid lipofuscinoses