CHSTE Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification SIAH2 encodes E3 ubiquitin-protein ligase

SIAH2 encodes E3 ubiquitin-protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family

It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability

Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin but calreticulin is not a Ro/SS-A antigen

and in the 3' UTR of transferrin receptor mRNA

Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8

CHSTE Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification SIAH2 encodes E3 ubiquitin-protein ligaseThis gene encodes a member of the HNK 1 family of sulfotransferases. The encoded protein transfers sulfate to the C 4 hydroxyl of N acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb clubfoot syndrome.