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DNA Ligase III Polyclonal Antibody, 100ul Roller Bottles providing valuable insights into immune

SKU: 27122946189

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DNA Ligase III Polyclonal Antibody, 100ul Roller Bottles providing valuable insights into immuneLIG3 is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon

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Description

providing valuable insights into immune response and inflammation

A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon

Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy

Mutations in this gene cause glycogen storage disease type 9A| also known as X-linked liver glycogenosis

Hematoregulatory chemokine| which| in vitro| suppresses hematopoietic progenitor cell proliferation

DNA Ligase III Polyclonal Antibody, 100ul Roller Bottles providing valuable insights into immuneLIG3 is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon

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