Tie-1 Polyclonal Antibody, 100ul Reagent Reservoirs It is proposed to serve

It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways

The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding

The N-terminal half of this protein is required for its centrosome localization and for its multimerization

ADGRE2 encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors

Gene Ontology (GO) annotations related to PDRG1 p53 include unfolded protein binding

Tie-1 Polyclonal Antibody, 100ul Reagent Reservoirs It is proposed to serveTIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1) encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth