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Porcine Plasminogen Activator Inhibitor 1, PAI-1 ELISA Kit, 96T Filtration Positively regulates TGFB1-mediated SMAD2/3 activation

SKU: 26264354778

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Porcine Plasminogen Activator Inhibitor 1, PAI-1 ELISA Kit, 96T Filtration Positively regulates TGFB1-mediated SMAD2/3 activationSerine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue type plasminogen activator (PLAT) and urokinase type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease

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Description

Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types

Each laminin chain is a multidomain protein encoded by a distinct gene

Certain mutations in this gene cause butterfly-shaped pigment dystrophy

GO annotations related to this gene include G-protein coupled receptor activity and complement component C5a binding

Impairs HCV replication via RNA editing at multiple sites

Porcine Plasminogen Activator Inhibitor 1, PAI-1 ELISA Kit, 96T Filtration Positively regulates TGFB1-mediated SMAD2/3 activationSerine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue type plasminogen activator (PLAT) and urokinase type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease

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