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CBX8 Polyclonal Antibody, 50ul Sampling Tubes ZNF337 encodes a zinc finger

SKU: 26206816630

4.1
SEK162.00 SEK191.00

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CBX8 Polyclonal Antibody, 50ul Sampling Tubes ZNF337 encodes a zinc fingerComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys 119', rendering chromatin heritably changed in its expressibility.,Contains 1 chromo domain.,subunit: Component of chromatin

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Description

ZNF337 encodes a zinc finger domain containing protein

In addition| the encoded protein interacts with LIS1| the regulatory gamma subunit of platelet activating factor acetylhydrolase| and this interaction is important to proper microtubule function in the developing cortex

The encoded protein has been implicated in several pathologic processes

The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules

Two alternatively spliced transcript variants encoding the same protein

CBX8 Polyclonal Antibody, 50ul Sampling Tubes ZNF337 encodes a zinc fingerComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys 119', rendering chromatin heritably changed in its expressibility.,Contains 1 chromo domain.,subunit: Component of chromatin

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