BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 20ul Lysosome with the black immuno-micro plate
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BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 20ul Lysosome with the black immuno-micro plateIntact BH3 motif is required by BIK BID BAK BAD and BAX for their pro apoptotic activity and for their interaction with anti apoptotic members of the Bcl 2 family. The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1 isoform 2 and isoform 4 induce ICE like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl 2. PTM: Phosphorylated upon DNA damage probably by
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