FXYD4 Rabbit Polyclonal Antibody, 50ul Plates & Dishes Intermediate filamentents

Intermediate filamentents

The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system

Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors

An important paralog of this gene is DNAL4

This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation

FXYD4 Rabbit Polyclonal Antibody, 50ul Plates & Dishes Intermediate filamententsThis gene encodes a member of a family of small membrane proteins that share a 35 amino acid signature sequence domain beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD domain containing ion transport regulator. FXYD4 originally named CHIF for channel inducing factor has been shown to modulate the properties of the Na K ATPase as has FXYD2 also