Rb Polyclonal Antibody, 50ul[BT-AP07694] Antibody Development A pseudogene of this gene

A pseudogene of this gene is found on chromosome 13

A pseudogene for this gene is located on chromosome 11q13

these tips ensure minimal sample loss and contamination

sequence-specific DNA binding and RNA polymerase II transcription coactivator activity

9 PCR Tube Adapter

Rb Polyclonal Antibody, 50ul[BT-AP07694] Antibody Development A pseudogene of this geneThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.