TGF Beta RI Polyclonal Antibody, 100ul Cell Culture Flasks This proto-oncogene

This proto-oncogene

|disease:Defects in CTSA are the cause of galactosialidosis

q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas

It contains a Sec7 domain

Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C

TGF Beta RI Polyclonal Antibody, 100ul Cell Culture Flasks This proto-oncogeneTGF beta receptor type 1 encoded by TGFBR1 forms a heteromeric complex with type II TGF beta receptors when bound to TGF beta, transducing the TGF beta signal from the cell surface to the cytoplasm. The TGF beta receptor type 1 is a serine threonine protein kinase. Mutations in this gene have been associated with Loeys Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.