Human Inter-alpha-trypsin Inhibitor Heavy Chain H2, ITIH2 ELISA Kit, 96T Human Genome Knockout Libraries benign neonatal type 1 (EBN1)

benign neonatal type 1 (EBN1)

Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease

The protein encoded by this gene is an inositol 1|4|5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain

Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro

The encoded protein also functions as an antiviral factor

Human Inter-alpha-trypsin Inhibitor Heavy Chain H2, ITIH2 ELISA Kit, 96T Human Genome Knockout Libraries benign neonatal type 1 (EBN1)May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.