DGAT1 Rabbit Polyclonal Antibody, 100ul Cell Culture Plates Knockout studies in mice suggest

Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior

Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract

Phosphorylation is induced by a wide range of stimuli| including growth factors| tumor-promoting agents| and mitogens

The encoded protein may play a role in breast cancer proliferation and chemoresistance

May also be involved in cardiac development

DGAT1 Rabbit Polyclonal Antibody, 100ul Cell Culture Plates Knockout studies in mice suggestThis gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases.