GRK 2 Monoclonal Antibody, 100ul Electrophoresis & Labeling Cells overexpressing ACAP1 and PIP5K1C

Cells overexpressing ACAP1 and PIP5K1C show formation of tubular structures derived from endosomal membranes

This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins

TORC1 binds to and is inhibited by FKBP12-rapamycin

Six pseudogenes

UV irradiation

GRK 2 Monoclonal Antibody, 100ul Electrophoresis & Labeling Cells overexpressing ACAP1 and PIP5K1CThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.