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Three transcript variants encoding two different isoforms have been found for this gene

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The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis

JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML)

Paxillin Polyclonal Antibody, 20ul[BT-AP06955] Custom Peptide Synthesis Take control of your experimentsPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.