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Phospho-AP-1 (T93) Polyclonal Antibody, 100ul Low retention tips The encoded protein is thought

SKU: 23054529897

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Phospho-AP-1 (T93) Polyclonal Antibody, 100ul Low retention tips The encoded protein is thoughtJUN is the putative transforming gene of avian sarcoma virus 17. It encodes Jun proto oncogene, AP 1 transcription factor subunit which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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Description

The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling

Multiple alternatively spliced transcript variants have been found| but the full-length nature of some variants has not been defined

The encoded protein may play a role in breast cancer proliferation and chemoresistance

Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions

The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis

Phospho-AP-1 (T93) Polyclonal Antibody, 100ul Low retention tips The encoded protein is thoughtJUN is the putative transforming gene of avian sarcoma virus 17. It encodes Jun proto oncogene, AP 1 transcription factor subunit which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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