GRB10 Polyclonal Antibody, 100ul Immune Cell Analysis The different subunits arise from

The different subunits arise from alternative splicing in the 3' coding region

The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component

It is involved in cell adhesion through trans-homophilic and -heterophilic interactions

a calmodulin-binding domain (CBD)

The encoded protein (BCL2 interacting protein 2) also interacts with E1B 19 kDa-like sequences of BCL2

GRB10 Polyclonal Antibody, 100ul Immune Cell Analysis The different subunits arise fromGrowth factor receptor bound protein 10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. GRB10 encodes a growth factor receptor binding protein that interacts with insulin receptors and insulin like growth factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. GRB10 is