PEAR1 Polyclonal Antibody, 50ul PCR Series The protein encoded by this

The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system

These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors)| permitting specific synaptic vesicle docking and fusion

SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins

Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC)

The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell

PEAR1 Polyclonal Antibody, 50ul PCR Series The protein encoded by thisPEAR1 is a platelet receptor that signals upon the formation of platelet platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005