LKB1 Polyclonal Antibody, 20ul[BT-AP05039] Cellular Function Assays Its two SH3 domains direct

Its two SH3 domains direct complex formation with proline-rich regions of other proteins

Excellent mixing (200-1500rpm)

Present in 80% of breast cancers

peripheral blood lymphocytes and bone marrow

This kinase is localized in the nucleus

LKB1 Polyclonal Antibody, 20ul[BT-AP05039] Cellular Function Assays Its two SH3 domains directSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been