ELP1 Rabbit Polyclonal Antibody, 100ul Micro Centrifuge Tubes Disruptions in this gene are

Disruptions in this gene are thought to be associated with neural tube defects

Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A

Members of this family play a role in cytoskeletal regulation

kidney and skeletal muscle

glutathione peroxidases are also involved in modulating these processes

ELP1 Rabbit Polyclonal Antibody, 100ul Micro Centrifuge Tubes Disruptions in this gene areThe protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF kappa B inducing kinase and I kappa B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.