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Phospho-Akt (S473) Polyclonal Antibody, 50ul[BT-PHS00864] Lentiviral Packaging a major risk factor for

SKU: 21412697240

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SEK162.00 SEK212.00

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Phospho-Akt (S473) Polyclonal Antibody, 50ul[BT-PHS00864] Lentiviral Packaging a major risk factor forThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

a major risk factor for coronary artery disease

the protein does not phosphorylate ceramide and its target substrate is currently unknown

The tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine

tissue specificity:Expressed chiefly in non-neuronal tissues

Three alternatively spliced transcript variants that encode different isoforms have been described for this gene

Phospho-Akt (S473) Polyclonal Antibody, 50ul[BT-PHS00864] Lentiviral Packaging a major risk factor forThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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