PIWL2 Rabbit Polyclonal Antibody, 20ul Microplate Mixer miscellaneous:The ancestral BAGE gene was

miscellaneous:The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins

The encoded preproprotein is proteolytically processed to generate the mature protease

and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis

and maps to human chromosome 12p12

PIWL2 Rabbit Polyclonal Antibody, 20ul Microplate Mixer miscellaneous:The ancestral BAGE gene wasPIWIL2 belongs to the Argonaute family of proteins which function in development and maintenance of germline stem cells (Sasaki et al. 2003