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AKAP 13 Polyclonal Antibody, 50ul Virus Packaging NFKB2 appears to have dual

SKU: 20916420054

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AKAP 13 Polyclonal Antibody, 50ul Virus Packaging NFKB2 appears to have dualThe A kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c terminal dbl oncogene homology (DH) and

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Description

NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing

May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis

with much higher expression in heart

alpha 1 subunit

which is present only in muscle tissues

AKAP 13 Polyclonal Antibody, 50ul Virus Packaging NFKB2 appears to have dualThe A kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c terminal dbl oncogene homology (DH) and

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