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FAK Monoclonal Antibody, 50ul[BT-MCA0527] Plasma These proteins contain pleckstrin homology

SKU: 20442459626

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FAK Monoclonal Antibody, 50ul[BT-MCA0527] Plasma These proteins contain pleckstrin homologyThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

These proteins contain pleckstrin homology (PH) domain

The protein encoded by EDA (ectodysplasin A) is a type II membrane protein that can be cleaved by furin to produce a secreted form

They have been implicated in some hereditary disorders

These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation

contain a tetratricopeptide repeat (TPR) domain

FAK Monoclonal Antibody, 50ul[BT-MCA0527] Plasma These proteins contain pleckstrin homologyThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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