CIS Polyclonal Antibody, 20ul Vortex Mixer and genomic duplication of a

and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51

RPS6KA5 (Ribosomal protein S6 kinase alpha-5) is a Protein Coding gene

This gene encodes a member of the dynein intermediate chain family

When exogenously expressed

The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency

CIS Polyclonal Antibody, 20ul Vortex Mixer and genomic duplication of aThe protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM CSF and EPO in hematopoietic cells.