PDC-E2 Monoclonal Antibody, 100ul Cell Separation and Collection The encoded protein cleaves ubiquitin

The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation

Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis

The protein encoded by this gene is similar to the yeast Mob1 protein

This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1)

The promoter of this gene is frequently hypermethylated in these cancer tissues| although the hypermethylation does not appear to be the cause of the reduced expression of this gene

PDC-E2 Monoclonal Antibody, 100ul Cell Separation and Collection The encoded protein cleaves ubiquitinThis gene encodes component E2 of the multi enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial