NTAN1 Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production Expression of ADCK2 inversely correlates

Expression of ADCK2 inversely correlates with cellular viability

and is required for endosome-to-Golgi transport

Contains 1 DHR-1 (CZH-1) domain

The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control

that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA

NTAN1 Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production Expression of ADCK2 inversely correlatesThe protein encoded by this gene functions in a step wise process of protein degradation through the N end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N terminal L Asn residues on proteins to produce N terminal L Asp. L Asp substrates are subsequently conjugated to L Arg which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of