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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression These optimized lentiviruses deliver efficient

SKU: 19808893099

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PLN141.00 PLN170.00

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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression These optimized lentiviruses deliver efficientThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

These optimized lentiviruses deliver efficient

The larger transcript is approximately 13

This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility

Several alternatively spliced transcript variants have been described for this gene

MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression These optimized lentiviruses deliver efficientThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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