Eps15(Phospho Tyr849) Polyclonal Antibody, 20ul Immune Cell Preparation Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants of AKR1A1 exist

Found in a complex with DLG4 and BEGAIN

The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex| which| along with TFIID| is required for efficient activation by SP1

and circadian rhythm

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Eps15(Phospho Tyr849) Polyclonal Antibody, 20ul Immune Cell Preparation Multiple alternatively spliced transcript variantsThis gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin coated pits and is involved in receptor mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX ALL MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.