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GLI-1 Polyclonal Antibody, 20ul Long RNA Synthesis a melanocyte-specific protein

SKU: 19165665483

4.3
EUR97.20 EUR144.20

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GLI-1 Polyclonal Antibody, 20ul Long RNA Synthesis a melanocyte-specific proteinThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

a melanocyte-specific protein

MX dynamin like GTPase 2 encoded by MX2 has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases

Alternatively spliced transcript variants have been identified for NBL1

The encoded protein is a highly specific ubiquitin iso-peptidase

mutations in this gene are thought to confer a predisposition to sarcomas

GLI-1 Polyclonal Antibody, 20ul Long RNA Synthesis a melanocyte-specific proteinThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

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