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Vav3(Phospho Tyr173) Polyclonal Antibody, 20ul Microplate Mixer The protein functions as a

SKU: 19127273728

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Vav3(Phospho Tyr173) Polyclonal Antibody, 20ul Microplate Mixer The protein functions as aThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide free states of these GTPases. Alternatively spliced transcript variants encoding

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Description

The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling functions

consisting of Polycomb and Heterochromatin Protein 1 genes

The dimer also associates with NARG1| and this complex binds to the osteocalcin promoter and activates osteocalcin expression

forming a channel that is permeable to calcium

The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine

Vav3(Phospho Tyr173) Polyclonal Antibody, 20ul Microplate Mixer The protein functions as aThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide free states of these GTPases. Alternatively spliced transcript variants encoding

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