Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 50ul Immune Cell Preparation BLCAP encodes a protein that

BLCAP encodes a protein that reduces cell growth by stimulating apoptosis

Alternatively spliced transcript variants encoding different isoforms have been described for this gene

and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton

This gene's protein is found in the cytoplasm| yet it lacks the nuclear localization signals found in other subfamily members

The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux

Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 50ul Immune Cell Preparation BLCAP encodes a protein thatThis gene encodes an anti apoptotic protein which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.