SAP18 Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The translocation produces a chimeric

The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of CBFA2T3

Binds to core DNA sequence 5'-

Phosphorylation at Tyr694 is obligatory for Stat5 activation

Neurensin-1 may play an important role in neural organelle transport

and hence is an inhibitor of fibrinolysis

SAP18 Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The translocation produces a chimericHistone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex which includes SIN3 SAP30 HDAC1 HDAC2 RbAp46 RbAp48 and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3 mediated transcriptional repression when tethered to the promoter. A