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AQP2 Polyclonal Antibody, 50ul Serum Not detected in brain and

SKU: 18206852775

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AQP2 Polyclonal Antibody, 50ul Serum Not detected in brain andAquaporin 2 (AQP2) is a water transport protein that forms water channels in kidney tubules and plays a predominant role in controlling organism water homeostasis. Mutations in the corresponding AQP2 gene cause a rare form of diabetes known as nephrogenic diabetes insipidus. This autosomal dominant disorder is characterized by abnormal water reabsorption by kidney tubules due, in part, to either nonfunctional or mislocalized AQP2 protein.

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Description

Not detected in brain and peripheral blood leukocytes

When exposed to insulin

FOXO4 encodes a member of the O class of winged helix/forkhead transcription factor family

GDF6 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules

This family member may also play a role in polyglutamine aggregation in specific neurons

AQP2 Polyclonal Antibody, 50ul Serum Not detected in brain andAquaporin 2 (AQP2) is a water transport protein that forms water channels in kidney tubules and plays a predominant role in controlling organism water homeostasis. Mutations in the corresponding AQP2 gene cause a rare form of diabetes known as nephrogenic diabetes insipidus. This autosomal dominant disorder is characterized by abnormal water reabsorption by kidney tubules due, in part, to either nonfunctional or mislocalized AQP2 protein.

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