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p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11723] RNA Synthesis Multiple transcript variants encoding at

SKU: 17544657673

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p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11723] RNA Synthesis Multiple transcript variants encoding atThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

Multiple transcript variants encoding at least two different isoforms have been described for this gene

In addition to its inhibitory role against most of the known MMPs

ADNP encodes activity dependent neuroprotector homeobox that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells

an essential enzyme in heme catabolism

This gene is expressed exclusively in the brain

p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11723] RNA Synthesis Multiple transcript variants encoding atThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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