PAX7 Polyclonal Antibody, 20ul Buffer Solutions The product of CAMK2A (calcium/calmodulin

The product of CAMK2A (calcium/calmodulin dependent protein kinase II alpha) belongs to the serine/threonine protein kinases family

Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene

This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation

A full-length representative protein consists of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain

This is supported by studies in knockout mice showing development of soft-tissue sarcomas| ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen

PAX7 Polyclonal Antibody, 20ul Buffer Solutions The product of CAMK2A (calcium/calmodulinThis gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated