ZNF420 Polyclonal Antibody, 100ul Peptide Library differentiation and survival and contain

differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites

This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q

A snoRNA gene (SNORD61) is found in one of its introns

Many of the subunits belong to a family called nucleoporins (Nups)

This PTP also suppresses JAK kinases

ZNF420 Polyclonal Antibody, 100ul Peptide Library differentiation and survival and containZinc finger protein 420 encoded by ZNF420 is a KRAB type zinc finger protein that negatively regulates p53 mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis.