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Beclin-1(Phospho-Ser15) Rabbit Polyclonal Antibody, 100ul Drying & Desiccation This gene is found in

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Beclin-1(Phospho-Ser15) Rabbit Polyclonal Antibody, 100ul Drying & Desiccation This gene is found inThis gene encodes a protein that regulates autophagy a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes including tumorigenesis neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

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Description

This gene is found in the large histone gene cluster on chromosome 6p22-p21

DDX52 is phosphorylated by ATM or ATR upon DNA damage

Mutations in this gene are associated with defects and cancers of the immune system

which is important in the protease network associated with inflammation

This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation

Beclin-1(Phospho-Ser15) Rabbit Polyclonal Antibody, 100ul Drying & Desiccation This gene is found inThis gene encodes a protein that regulates autophagy a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes including tumorigenesis neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

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