NBK Polyclonal Antibody, 100ul Culture Tubes An important paralog of this

An important paralog of this gene is R3HCC1

but lacks the active site lysine and probably lacks a catalytic function

It is encoded by 6 exons

Catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol

With its durable construction and precise design

NBK Polyclonal Antibody, 100ul Culture Tubes An important paralog of thisBcl 2 interacting killer encoded by BIK shares a critical BH3 domain with other death promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro apoptotic activity, and for interaction with anti apoptotic members of the BCL2 family, and viral survival promoting proteins. Since the activity of this protein is suppressed in the presence of survival promoting proteins, it is suggested as a likely target for anti apoptotic proteins.