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P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 100ul sgRNA Oligos The encoded protein may function

SKU: 17067382093

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P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 100ul sgRNA Oligos The encoded protein may functionThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

The encoded protein may function in renal tubular development and function

It is highly similar to Saccharomyces cerevisiae Cdc14

|Belongs to the type IV collagen family

The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding

probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases

P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 100ul sgRNA Oligos The encoded protein may functionThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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