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p300 Polyclonal Antibody, 100ul[BT-AP06775] Site-directed Mutagenesis Mutations in this gene have

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p300 Polyclonal Antibody, 100ul[BT-AP06775] Site-directed Mutagenesis Mutations in this gene haveEP300 encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co activator of HIF1A (hypoxia inducible factor 1 alpha), and

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Description

Mutations in this gene have been associated with bone marrow failure syndrome 2

The protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR)

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The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled

p300 Polyclonal Antibody, 100ul[BT-AP06775] Site-directed Mutagenesis Mutations in this gene haveEP300 encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co activator of HIF1A (hypoxia inducible factor 1 alpha), and

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