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NACA Polyclonal Antibody, 20ul Vortex Mixer Mutations in this gene have

SKU: 16516297779

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NACA Polyclonal Antibody, 20ul Vortex Mixer Mutations in this gene haveThis gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative

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Description

Mutations in this gene have been associated with acral peeling skin syndrome

This member is identified as a 'silent subunit'

Defects in this gene can result in three different disorders

fetal brain and fetal kidney

NME1 (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells

NACA Polyclonal Antibody, 20ul Vortex Mixer Mutations in this gene haveThis gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative

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