Z280B Polyclonal Antibody, 100ul Microplate Mixer Notch family members play a

Notch family members play a role in a variety of developmental processes by controlling cell fate decisions

The encoded protein is part of the nuclear pore complex and is anchored there by NDC1

It is widely distributed in peripheral organs| such as liver and kidney| and is also present in low amounts in the central nervous system

TYK2 encodes a member of the tyrosine kinase and

GABARAPL2 (also known as Golgi-associated ATPase enhancer of 16 kDa

Z280B Polyclonal Antibody, 100ul Microplate Mixer Notch family members play aThe protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein coding.