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IkB alpha Rabbit Polyclonal Antibody, 50ul Protein Modification This protein is a member

SKU: 16053057079

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IkB alpha Rabbit Polyclonal Antibody, 50ul Protein Modification This protein is a memberThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

This protein is a member of the Stac gene family and contains an N-terminal cysteine-rich domain and two SH3 domains

G-protein coupled receptor (GPCR) family

and may be involved in leukocyte trafficking

The protein encoded by this gene is a type IV membrane protein

tissue specificity:Seems to be expressed in prostate and less abundantly in adult brain

IkB alpha Rabbit Polyclonal Antibody, 50ul Protein Modification This protein is a memberThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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