Stat4(Phospho Tyr693) Polyclonal Antibody, 100ul[BT-AP14540] Culture Tubes It is thought to form

It is thought to form either a homodimer or heterodimer

The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations

are observed frequently in a variety of tumors and may contribute to tumorigenesis

The protein is implicated in several signal transduction pathways including the Stat pathway

and may modify the risk of Alzheimer's disease

Stat4(Phospho Tyr693) Polyclonal Antibody, 100ul[BT-AP14540] Culture Tubes It is thought to formThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.